Papaya Leaf Has The Caffeic Acid That Battles Prostate and Breast Cancer

Of the list of cancer-fighting phytochemicals found in papaya leaf, Caffeic Acid has been shown as the most abundant of any in the papaya leaf, and significantly more abundant in the leaf than in any other part of the papaya plant including the fruit.

-Proximate Analysis, Antioxidant and Anti Proliferative Activities of Different Parts of Carica papaya Maisarah AM1, Asmah R1 and Fauziah O2, 1Department of Nutrition and Dietetics, Universiti Putra Malaysia, Malaysia 2Department of Human Anatomy, Universiti Putra Malaysia, Malaysia

What is significant about this is that Caffeic acid has shown effect on fighting specifically Prostate and Breast cancer. Its use is also as a complement to standard drugs like Tamoxifen. See the selected studies below.

Prostate Cancer:

Breast Cancer:

Papaya Leaf Shows Anti-Proliferative Effect on Prostate Cancer Cells

DOI: 10.1111/bju.13198
Conference: Prostate Cancer World Congress-August, 2015, At Cairns Convention Centre, Australia

“This study has shown that anti-Proliferative responses to papaya [leaf juice] extracts.”

Carica papaya leaf juice extracts have selective anti-proliferative responses in prostatic disease

This blog sponsored by the Julia Ruffin Project: researching, promoting, and growing papaya leaves for cancer

Papaya Leaf Tea Changed His PSA, Says California Man

Letter to the Blogger:

In 2002 I was diagnosed with prostate cancer. I chose to treat my cancer with proton radiation.
In the fall of 2009 my PSA went up and the prostate biopsy again came up positive.
In January I had cryoablation treatment of the prostate and within weeks my PSA went even higher.
At that point tests were performed that showed the cancer had spread to the lymph nodes. At the recommendtion of the urologist I went on hormone therapy (Lupron). The side effects from the hormone treatment were not pleasant.
In August of 2013 friends told me about papaya leaf tea for cancer and I started drinking the tea that month. My last hormone treatment was April 2014. My PSA test in December 2014 was 0.633.
My urologist could not believe the test as the last time I went 8 months without the hormones my PSA went to 66.
The only explanation for this amazing result is Papaya Leaf Tea.
Thank you Virginia for the input and encouragement that you have given me for drinking the tea.”

We have not published the name of this man but will release his name for specific requests with his permission after a review of the reason for the request. Send in a request and reason to

The Julia Ruffin Project promotes, researches, and test-farms papaya leaf tea.

Anti-Tumor Components in Papaya Leaf

“The ability of phytochemicals to inhibit tumor formation both in vitro and in vivo is well documented.”

Ichikawa, H., Nakamura, Y., Kashiwada, Y., and Aggarwal, B.B. Anticancer drugs designed by mother nature: Ancient drugs but modern targets. Curr. Pharm. Des 13, 3400–3416 (2007)

“Many of these [phytochemical] compounds have anti-oxidant, anti-proliferative, and pro-apoptotic effects on a variety of cancers, including leukemia, prostate, breast, colon, brain, melanoma, and pancreatic. Moreover, cancer stem cells have been identified for each of these blood and solid tumors paving the way for future studies to evaluate the efficacy of phytochemicals against cancer stem cells. The benefit of many of these phytochemicals is that they are well tolerated and are found in many food products that can be added to one’s diet. Furthermore, phytochemicals could be taken on a long-term basis to either prevent primary tumor formation or tumor recurrence.”

-Targeting Cancer Stem Cells with Phytochemicals
Brian T. Kawasaki, Elaine M. Hurt, Tashan Mistree and William L. Farrar

Papaya leaves contain a blend of phytochemicals named the “Kit for Cancer”.

“In the leaves of Carica papaya, components previously reported to potentially have anti-tumor activity include: tocopherol, lycopene, flavonoid, and benzylisothiocyanate.”

According to researchers:
Noriko Otsukia, Nam H. Dangb, Emi Kumagaia, Akira Kondoc, Satoshi Iwataa, Chikao Morimotoa
Aqueous extract of Carica papaya leaves exhibits anti-tumor activity and immunomodulatory effects

Related Posts on the effect of Papaya Leaf on Tumors

This post is for NJ’s friend.
The Julia Ruffin Project promotes, researches, and grows papaya leaf tea.