Papaya Leaf Shows Effect on Skin Cancer in Lab

A very special publication on Christmas Eve, 2015 shows the hard work in Australia to prove the inhibitive effect of papaya leaf on the second most common type of skin cancer, squamous cells.

” In this study, we investigated the in vitro cytotoxicity of aqueous and ethanolic extracts of Carica papaya leaves on the human oral squamous cell carcinoma SCC25 cell line in parallel with non-cancerous human keratinocyte HaCaT cells. Two out of four extracts showed a significantly selective effect towards the cancer cells and were found to contain high levels of phenolic and flavonoid compounds…

The principal compounds [in papaya leaf] identified were flavonoids or flavonoid glycosides, particularly compounds from the kaempferol and quercetin families, of which several have previously been reported to possess anticancer activities. These results confirm that papaya leaf is a potential source of anticancer compounds and warrant further scientific investigation to validate the traditional use of papaya leaf to treat cancer.”

Chemical Characterization and in Vitro Cytotoxicity on Squamous Cell Carcinoma Cells of Carica Papaya Leaf Extracts
Thao T. Nguyen 1, Marie-Odile Parat 1, Mark P. Hodson 1,2, Jenny Pan 1, Paul N. Shaw 1 and Amitha K. Hewavitharana 1,*
Received: 26 October 2015; Accepted: 18 December 2015; Published: 24 December 2015 Academic Editor: Carmela Fimognari


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