Enzyme in Papaya Leaf, Papain, Inhibits Tumor Growth and Metastatis in Lab

Proteolytic Enzyme Therapy for cancerous tumors goes back to the success of Dr Beard in 1910 (Enzyme Therapy for Cancer). He retrieved the trypsin (a proteolytic enzyme) from young cows and injected it straight into the patient’s Tumor. This method showed success. Doctors who subsequently tried to mimic this procedure were discredited but they tried to retrieve trypsin from old cows, which by definition have less pancreatic enzymes due to their age. The theory of an “enzyme bank” that decreases as we age belongs to Dr Edward Howell, who proved this in a series of studies over years. (1945 +)

The enzyme in papaya leaves, papain, is a proteolytic enzyme that also seems to show a similar effect on tumors, as in this animal study below. Papain is a more potent proteolytic enzyme than our body’s trypsin.

Inhibition of tumor growth, invasion and metastasis in papain-immunized mice.

Authors
Bellelli A, Mattioni M, Rusconi V, Sezzi ML, Bellelli L.
Journal
Invasion Metastasis. 1990;10(3):142-69.

“The growth rate, invasion and metastasis of both the B16 melanoma and the Lewis lung carcinoma were inhibited in mice immunized with papain. These animals presented an increased mean survival time as compared to the tumor-bearing nonimmunized controls. Quantitative microscopy suggested that vasodilation and edema, associated with tumor invasion, are, at least partially, sustained by proteolytic enzymes, being strongly reduced when tumor cells were inoculated in papain-immunized mice.”

http://www.ncbi.nlm.nih.gov/m/pubmed/2139872/

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s