Tannins in Papaya Leaf Tea Contribute to Weight Loss

According to a study in Spain, the tannins and saponins in papaya leaf tea inhibit our pancreatic lipases. Lipases are fat-digesting enzymes. Inhibiting lipases can contribute to weight loss, as discussed in the research below.

Natural inhibitors of Pancreatic Lipase as new players in obesity treatment

Authors: de la Garza AL, Milagro FI, Boque N, Campion J, Martinez JA
Ana Laura de la Garza, Fermín I.Milagro, Noemí Boque, Javier Campión, J.Alfredo Martínez
Affiliation
Department of Nutrition and Food Science, Physiology and Toxicology, University of Navarra, Pamplona, Spain

A number of studies have revealed various health benefits of plant polyphenols and their importance in foods, beverages and natural medicine. In this context, polyphenols have some potential efficacy for preventing obesity. They inhibit enzymes related to fat metabolism including PL, lipoprotein lipase, and glycerophosphate dehydrogenase [74]. Polyphenol extracts are able to decrease the blood levels of glucose, triglycerides and LDL cholesterol, increase energy expenditure and fat oxidation, and reduce body weight and adiposity [75,76]. In fact, many polyphenols, including flavones, flavonols, tannins and chalcones, have shown an inhibitory activity of PL [9,22].
Flavonoids are a type of plant secondary metabolites which are characterized as containing two or more aromatic rings, each bearing at least one aromatic hydroxyl and connected with a carbon bridge [76]. Some of them are polymerized into large molecules, either by the plants themselves or as a result of food processing. These polymers are called tannins and three subclasses (condensed tannins, derived tannins and hydrolysable tannins) exhibit a variety of beneficial effects on health [76].

Saponins
Saponins are a major family of secondary metabolites that occur in a wide range of plants species [106]. These compounds have been isolated from different parts of the plants, including the roots, rhizomes, stems, bark, leaves, seeds and fruits. Occasionally, the whole plant has been used [107].

Saponins are categorized into two major classes, the triterpenoid and the steroid saponins, which are both derived from the 30 carbon atoms-containing precursor oxidosqualene [107,108]. Some of the triterpene-rich plant materials are common foodstuffs consumed in large amounts in Mediterranean countries. Therefore, the correlation of a triterpene-rich diet and the beneficial effects of consuming a Mediterranean diet should be investigated in more detail [32].

These types of plant secondary metabolites are found to inhibit PL and, thus, may represent potential effective treatments for obesity and related disorders [9,22]. One example are different saponins isolated from tea [85] or ginseng [109].

-http://dspace.unav.es/dspace/bitstream/10171/19075/2/Planta%20medica2011.pdf

Papaya Leaf Tea is rich in tannins and saponins. Detailed analysis of this is in the research below:

http://www.ijlbpr.com/jlbpradmin/upload/ijlbpr_51d451cde89e7.pdf

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The Kit for Cancer (Phytochemicals) most Available from Crushed, Dried Papaya Leaves (Tea)

International Journal of Life Sciences Biotechnology and Pharma Research
July, 2013 Hyderabad, India
PHYTOCHEMICAL ANALYSIS OF PAW-PAW (CARICA PAPAYA) LEAVES
Ikeyi Adachukwu P1*, Ogbonna Ann O1 and Eze Faith U1

Phytochemicals are chemical compounds that occur naturally in plants. They are characterized by multilateral pharmacological activity and broad spectrum of therapeutic actions. The qualitative phytochemical analysis of Carica papaya leaves showed the presence of alkaloid, flavonoid, Saponin, Tannin and Glycosides [Kit for Cancer]. The qualitative test was justified by their color changes with their various reagents.

It is therefore, concluded that Carica papaya leaves contain Alkaloid, Saponin, Tannin, Glycoside and Flavonoids [Kit for Cancer] and this is in agreement with the work of [Willson et al., 2007]. Also, from the result, it can be deduced that phytochemicals can be extracted more when the leaves are dried and pulverized to powered form. To this, it then means that phytochemicals can be made available commercially. The study has shown that Carica papaya can be seen as a potential source of useful food and drug items.

-http://www.ijlbpr.com/jlbpradmin/upload/ijlbpr_51d451cde89e7.pdf

Pakistan Researchers Prove Effect of Papaya Leaf on Dengue Infected Man

-http://www.jpma.org.pk/full_article_text.php?article_id=6137

20140403-212558.jpg

March, 2014

Effects of papaya leaves on thrombocyte counts in dengue – a case report
Pages with reference to book, From 364 To 366
Osama Siddique, Ayesha Sundus ( Student, Dow University of Health Sciences, Karachi. )
Mohammad Faisal Ibrahim ( Civil Hospital Karachi. )

Introduction
Carica papaya L. is the only species within the Caricaceae genus, and the palm-like tree has segmented leaves, yellow flowers and large black seeded yellow to orange fruits.1 C. papaya L. fruit juice and leaves extracts have demonstrated anti-cancer,2 anti-oxidative,3 anti-inflammatory,4 anti-bacterial,5 nephro-protective,6 hepato-protective7 activity against toxins, hypoglycaemic, hypolipidaemic effects8 and anti-sickling properties in sickle cell disease.9
Dengue fever (flaviviridae family of viruses) is an arthropod-borne disease carried by Aedes ayegypti with four different serotypes 1, 2, 3 and 4.10 Dengue fever cases have been on the rise in Pakistan and other developing countries. It is estimated that there are between 50 and 100 million cases of dengue fever (DF) and about 500,000 cases of dengue haemorrhagic fever (DHF) each year which require hospitalisation.10 There is no known anti-viral chemotherapy for DF yet. Many vaccine trials have been done, but none has produced a satisfactory outcome.10 Management includes supportive measures like anti-pyretic, hydration, blood and blood products and pain killers. Infection induces a life-long immunity to that particular serotype, but secondary infection with another serotype is dangerous and life-threatening due to higher risks of DHF.11 The only way to prevent dengue virus acquisition is to avoid being bitten by a vector mosquito.10
With such high rates of incidence and mortality it would be useful to have a regimen improving the outcome of the disease. Investigating the effect of papaya leaves on the platelets can help our physicians in helping patients with diseases like DF where the platelets are the major cause of complications and mortality. Here we present a DF case who responded positively to the administration of papaya leaves extract.