Link Between Diabetes and Cancer calls for Papaya Leaf Healing

“Diabetes has been consistently associated with increased risk of several of the more common cancers”, and for this reason the American Cancer Society commissions studies on the links and causal relationship between the two diseases which represent the second and seventh most common form of death in the US, according to a recent consensus study on the issue.


For this reason the Julia Ruffin Project is keenly interested in how the papaya leaf affects diabetes, and we want to pay tribute to a study on the long-term anti-diabetic effect of papaya leaves on rats with the disease.

According to the abstract of the study:

Treatment of STZ diabetic rats with C. papaya leaf extract produced significant (P<.05) reductions in FBS from week 2 of treatment. Normoglycaemia was attained in week 8 and sustained till week 24. Significant (P<.05) reductions in serum total cholesterol and LDL-cholesterol concentrations were also observed for most of the points monitored while HDL-cholesterol was significantly (P<.05) increased. The high AI and CRI caused by STZ diabetes was significantly (P<.05) reduced in the C. papaya treated diabetic rats.

The findings from this study substantiate the long term potential and traditional usage of C. papaya for antidiabetic and antihyperlipidaemic effects.

Long Term Anti-Diabetic, Anti-Hyperlipidaemic and Anti-Atherogenic Effects of Carica papaya Leaves in Streptozotocin Diabetic Rats

Omonkhua Akhere A.1*, Onoagbe Iyere O.2, Ajileye Afolabi F.3, Aladegboye Lekan O.3 and Adetoboye Ayodeji R

Published in
European Journal of Medicinal Plants 3(4): 508-519, 2013
SCIENCEDOMAIN international



Clinical Trial of 226 Dengue Patients in Malaysia Stars the Papaya Leaf


Research from Malaysia published less than a year ago shows in clinical trials with a decent size sample set that the papaya leaf has effect against Dengue fever.

We can’t help but celebrate with these scientists the results of their research:

Research Article
Carica papaya Leaves Juice Significantly Accelerates the Rate of Increase in Platelet Count among Patients with Dengue Fever and Dengue Haemorrhagic Fever

Soobitha Subenthiran,1 Tan Chwee Choon,2 Kee Chee Cheong,3 Ravindran Thayan,4 Mok Boon Teck,1 Prem Kumar Muniandy,1 Adlin Afzan,1 Noor Rain Abdullah,1 and Zakiah Ismail1
1Bioassay Unit, Herbal Medicine Research Center, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia
2Department of Internal Medicine, Tengku Ampuan Rahimah Hospital, Jalan Langat, 41200 Klang, Malaysia
3Epidemiology and Biostatistics Unit, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia
4Virology Unit, Infectious Disease Research Center, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia
Received 7 January 2013; Revised 21 March 2013; Accepted 21 March 2013
Academic Editor: Martin Kohlmeier
Copyright © 2013 Soobitha Subenthiran et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The study was conducted to investigate the platelet increasing property of Carica papaya leaves juice (CPLJ) in patients with dengue fever (DF). An open labeled randomized controlled trial was carried out on 228 patients with DF and dengue haemorrhagic fever (DHF). Approximately half the patients received the juice, for 3 consecutive days while the others remained as controls and received the standard management. Their full blood count was monitored 8 hours for 48 hours. Gene expression studies were conducted on the ALOX 12 and PTAFR genes. The mean increase in platelet counts were compared in both groups using repeated measure ANCOVA. There was a significant increase in mean platelet count observed in the intervention group () but not in the control group 40 hours since the first dose of CPLJ. Comparison of mean platelet count between intervention and control group showed that mean platelet count in intervention group was significantly higher than control group after 40 and 48 hours of admission (). The ALOX 12 (FC  =  15.00) and PTAFR (FC  =  13.42) genes were highly expressed among those on the juice. It was concluded that CPLJ does significantly increase the platelet count in patients with DF and DHF.

– Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 616737, 7 pages