Papain in Papaya Leaf has Potential for Tumors; Breast Cancer

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The Scottish Doctor John Beard discovered that by injecting the proteases taken from a young calf into a cancerous human tumor his patients could be cured.

Research in Brazil on the protease papain (can be taken from the raw papaya fruit or the leaves of the papaya tree) shows a potential contemporary use of papain on implant surgery to prevent painful fibrous buildup.

This is similar action to Dr Beard’s thinking centuries ago to inject a cancerous, fibrous tumor with a protein dissolving enzyme. It seems this action may also have systemic effect via the bloodstream, as Dr Nam Dang proved similar effect on tumors as well from the action of papaya leaf tea.

See the Brazilian study from 2008:

INTERNATIONAL JOURNAL OF BIOLOGY AND BIOMEDICAL ENGINEERING

“The capsular contracture is the most common adverse effect after breast implant [1]. Fibrotic tissue promotes compression around the implant which distorts and deforms the mass which then compromises the aesthetic result and is associated with painful symptoms [2]-[4]. The development of a fibrotic capsule around foreign material is a physiologic reaction of the organism to protect itself from material it does not recognize [5]. The severity of capsule contracture is directly related to the degree of the local inflammatory reaction [6] and does not depend on the implant surface employed [7]. Although it is not clear the pathogenesis of capsular contracture, this phenomenon seems to be multifactorial [8].
Currently, there is no effective preventive measure for capsule contracture [8]. The conventional treatment may be surgical, by capsulectomy (or capsulotomy) or implant replacement and pharmacological using steroids, anti- leukotrienes, anti-TGF-β, antibiotics or antiinflamatories [2], [3].
Up to now there has been no accurate and reproducible pathologic model for examining capsular contracture [9]. This study assumes that eventual interference by papain (PA) on normal healing could be useful in further studies of a more complex model with induced capsule contracture [9].
Some authors have speculated on the possible modulator action of certain proteolytic enzymes present around the implants in the early stages of healing [10], [11].
Papain is a thiol endopeptidase plant whose activity is similar to the lysosomal cathepsin B enzyme with fibrinolytic and proteolytic action on the normal healing mechanism [12].
It has been suggested that the papain could be helpful when used locally around the implant at the surgical procedure, promoting tissue repair with less fibrotic tissue, thus avoiding the capsule contracture.
The aim of this study was to investigate the papain effects on the fibrous capsule thickness, collagen fibers density and myofibroblasts around textured implants in rats.
Abstract— Objective: To study the tissue repair around the textured mammary implants under the action of papain (PA). Conclusion: The papain drug decreased the fibrous capsule formation around the textured silicon implants in rats.”

The papain local depot impairs the capsule fibrous healing around textured silicone implants in rats.
Marcio Moreira, Djalma José Fagundes, Sanderland José Tavares Gurgel

http://www.naun.org/main/NAUN/bio/19-152.pdf

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One thought on “Papain in Papaya Leaf has Potential for Tumors; Breast Cancer

  1. Pingback: Egypt and South Africa: Papaya “aerial parts” Show Effect Against Breast Cancer in Lab | Papaya Leaf Tea for Cancer

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