Pakistan Scientists Show Papaya Leaf Potential for Infectious Disease Breakthrough

A new 2013 publication in the International Research Journal of Pharmacy tested papaya leaf “tea” and papaya leaf extract on various pathogenic fungi (fungi that cause disease in humans) to show its potential to counter infectious diseases especially against drug resistant microbes. Both the tea and the extract showed effect against six saprophytic (parasites on the fungus on dead matter-not directly on dead matter) fungi. We thank the researchers below:

Sikandar Khan Sherwani, Tasveer Zahra Bokhari, Kanwal Nazim, Syed Aneel Gilani, Shahana Urooj Kazmi. Qualitative Phytochemical Screening and Antifungal Activity of Carica Papaya Leaf Extract Against Human and Plant Pathogenic Fungi

http://www.irjponline.com/admin/php/uploads/1897_pdf.pdf

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Papaya Leaf Tea to Relieve Side-Effects From Chemotherapy

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On the world renowned cancer clinic Memorial Sloan Kettering site:

“Clinical Summary:
Papaya tree is commonly found in tropical areas around the world. The fruits are consumed as food and as medicine; dried and powdered stem and leaves are used to prepare medicinal teas against infections and to improve digestion. Papaya leaves and their extracts are also marketed as dietary supplements to enhance the immune system, to improve platelet function, and to prevent chemotherapy-related adverse effects.
Papaya leaves exhibit anti-tumor, immunomodulatory (1), and antioxidant(9) effects in vitro.
The leaf extracts contain antibacterial compounds that inhibit the growth of a wide variety of Gram-positive and Gram-negative bacteria (4).
In mice, a powdered suspension of papaya leaves increased thrombocyte count (2) and a water extract reduced alcohol-induced stomach damage (5). Hypoglycemic effects were also reported with use of papaya leaf extract in streptozotocin-induced diabetic rats (10).

According to a case report, a water extract of papaya leaves was shown to increase the platelet count of a patient with Dengue fever (3)….”

-http://www.mskcc.org/cancer-care/herb/papaya-leaf

Feuilles de papaye pour le cancer
Papaya Blätter für Krebs
البابايا يترك للسرطان
Papaya Hojas para el cáncer
木瓜葉癌症
Papaya Dahon para sa Cancer
पपीता कैंसर के लिए पत्तियां
파파야는 암 잎
Folhas de papaia para o cancro
Листья папайи для Рака
パパイヤは、がんのために葉
Papaya levelek a rák
Daun betik untuk Kanser
پاپایا برگ برای سرطان
มะละกอใบสำหรับโรคมะเร็ง
Papai Majani ya Saratani ya
Papaya blare vir Kanker
Foglie di papaia per il cancro
Παπάγια Φύλλα για τον καρκίνο
Pepaya Daun untuk Kanker
Papaya Kanser bırakır

papaya hoja quimioterapia,
daun pepaya kemoterapi,
البابايا ورقة العلاج الكيميائي,
Papaya Blatt Chemotherapie,
木瓜叶化疗,
papaya blaar chemoterapie,
պապայա տերեւ chemotherapy,
papája list chemoterapie,
papaya blad kemoterapi,
papaya blad chemotherapie,
papaya dahon chemotherapy,
chimiothérapie feuille de papaye,
Τα φύλλα παπάγια χημειοθεραπεία,
פפאיה עלה כימותרפיה,
पपीता पत्ता कीमोथेरेपी,
papaya levél kemoterápia,
papaia foglia chemioterapia,
パパイヤの葉療法,
파파야 잎 화학 요법,
برگ پاپایا شیمی درمانی,
листьев папайи химиотерапии,
papaya yaprak kemoterapi,
پپیتا پتی کیموتیریپی

Fermented Papaya Leaves and Fermented Green Papaya Share Healing Power

Green Papaya fruit and papaya leaves (and seeds) share a set of enzymes called papain and chymopapain. These substances are so powerful that they have been commercially fermented and then marketed as healing for HIV, Cancer, Parkinson’s, Cyanocobalamin absorption in alcoholics and more.

Sun O in Japan offers a product named Bionormalizer.
http://www.bio-normalizer.com/english/no11/papaya/enzyme.html

Rochway, AU offers
Innun Prolog
http://www.rochway.com.au/product-categories/fermented-papaya-probiotics.html

Osato Japan offers
Innun’ Age F.P.P.
http://www.osatousa.com/

see more at
http://www.papayaleavesforcancer.com/fermentedpapaya.html

Contact Us if Your Company Manufactures or Distributes Pure Papaya Leaf Products

Contact Us, the Julia Ruffin Project
If your company is a manufacturer or distributor of papaya leaves.

We will do our best to promote your company. We want papaya leaves and papaya leaf products to be accessible to the world. Our goal is that people can use these leaves for healing.

Meet us at:
http://www.papayaleavesforcancer.com/contactus.html

There is a very simple form to fill out.

Papaya Leaves for Cancer

The Julia Ruffin Project
Researches, Grows, and promotes Papaya Leaf Tea.

Papaya leaf tea has shown effect against cancers in the lab. Proteases (protein dissolving enzymes) have shown effect against cancers in clinical studies on humans. Papain in the leaf is a protease and has also shown effect against cancers in the lab.

See more about the project at:

http://www.papayaleavesforcancer.com

If you are a papaya leaf manufacturer, please contact us:

info@papayaleavesforcancer.com
Include your country, a picture of your branding, and a distribution contact.

Feuilles de papaye pour le cancer
Papaya Blätter für Krebs
البابايا يترك للسرطان
Papaya Hojas para el cáncer
木瓜葉癌症
Papaya Dahon para sa Cancer
पपीता कैंसर के लिए पत्तियां
파파야는 암 잎
Folhas de papaia para o cancro
Листья папайи для Рака
パパイヤは、がんのために葉
Papaya levelek a rák
Daun betik untuk Kanser
پاپایا برگ برای سرطان
มะละกอใบสำหรับโรคมะเร็ง
Papai Majani ya Saratani ya
Papaya blare vir Kanker
Foglie di papaia per il cancro
Παπάγια Φύλλα για τον καρκίνο
Pepaya Daun untuk Kanker
Papaya Kanser bırakır

Canadians Show Papaya Mosaic Virus Creates Lung Immunity From Influenzas.

http://www.ncbi.nlm.nih.gov/m/pubmed/23499666/

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Canadian scientists have turned what the papaya industry producers have considered a “plague”, papaya mosaic virus (PAPmv) into a potential vaccine to protect against new influenza or bioterrorism…

Induction of innate immunity in lungs with virus-like nanoparticles leads to protection against influenza and Streptococcus pneumoniae challenge.

AuthorsMathieu C, et al. Show all Journal
Nanomedicine. 2013 Mar 8. pii: S1549-9634(13)00075-0. doi: 10.1016/j.nano.2013.02.009. [Epub ahead of print]

Affiliation
Department of Microbiology, Infectiology and Immunology, Infectious Disease Research Centre/CHU de Québec, Laval University, Laurier, Quebec City, PQ, Canada.

Abstract
Nanoparticles composed of the coat protein of a plant virus (papaya mosaic virus; PapMV) and a single-stranded RNA (ssRNA) trigger a strong innate immune stimulation in the lungs of the animals a few hours following instillation. A rapid recruitment of neutrophils, monocytes/macrophages and lymphocytes follows. This treatment was able to provide protection to an influenza challenge that lasts at least 5days. Protection could be recalled for longer periods by repeating the instillations once per week for more than 10weeks. The treatment also conferred protection to a lethal challenge with Streptococcus pneumoniae – the major cause of bacterial pneumonia. Finally, we also showed that the nanoparticles could be used to treat mice infected with influenza and significantly decrease morbidity. These data strengthen the potential for using PapMV nanoparticles as non-specific inducers of the innate immune response in lungs during viral pandemics or to combat bioterrorist attack.

http://www.ncbi.nlm.nih.gov/m/pubmed/23499666/

Papaya Leaf Relief for Chikungunya Virus

Chikungunya virus infection can cause a debilitating illness, most often characterized by fever, headache, fatigue, nausea, vomiting, muscle pain, rash, and joint pain. The term ‘chikungunya’ means ‘that which bends up’ in the Kimakonde language of Mozambique.

Acute chikungunya fever typically lasts a few days to a few weeks, but as with dengue, West Nile fever and other arboviral fevers, some patients have prolonged fatigue lasting several weeks. Additionally, some patients have reported incapacitating joint pain, or arthritis which may last for weeks or months. The prolonged joint pain associated with chikungunya virus is not typical of dengue. No hemorrhagic cases related to chikungunya virus infection have been conclusively documented in the scientific literature. Co-circulation of dengue fever in many areas may mean that chikungunya fever cases are sometimes clinically misdiagnosed as dengue infections, therefore the incidence of chikungunya fever could be much higher than what has been previously reported. -CDC

http://www.cdc.gov/chikungunya/symptoms/index.html

Studies show that relief from the virus can come by drinking papaya leaf juice or papaya leaf tea as it raises back white blood cell count. See the related below:

https://papayaleaves.wordpress.com/2014/10/04/ayurvedic-medicine-recommends-papaya-leaf-for-chikungunya-virus/

https://papayaleaves.wordpress.com/2014/10/16/pilot-study-white-cell-count-increases-with-papaya-leaf-juice/

Relief from the virus can also come by getting rid of the Mosquitos who carry it. The study below from Bharathiar University India is to test papaya leaf effect as an insecticide on the the Aedes aegypti mosquito which transmits the Chikungunya virus.

Bioefficacy of larvicdial and pupicidal properties of Carica papaya (Caricaceae) leaf extract and bacterial insecticide, spinosad, against chikungunya vector, Aedes aegypti (Diptera: Culicidae).

Kalimuthu Kovendan, Kadarkarai Murugan, Arjunan Naresh Kumar, Savariar Vincent, Jiang-Shiou Hwang
Division of Entomology, Department of Zoology, School of Life Sciences, Bharathiar University, Coimbatore, 641 046 Tamil Nadu, India.
Parasitology Research (impact factor: 2.15). 07/2011; 110(2):669-78. DOI:10.1007/s00436-011-2540-z
Source: PubMed

ABSTRACT The present study was carried out to establish the properties of Carica papaya leaf extract and bacterial insecticide, spinosad on larvicidal and pupicidal activity against the chikungunya vector, Aedes aegypti. The medicinal plants were collected from the area around Bharathiar University, Coimbatore, India. C. papaya leaf was washed with tap water and shade-dried at room temperature. An electrical blender powdered the dried plant materials (leaves). The powder (500 g) of the leaf was extracted with 1.5 l of organic solvents of methanol for 8 h using a Soxhlet apparatus and then filtered. The crude leaf extracts were evaporated to dryness in a rotary vacuum evaporator. The plant extract showed larvicidal and pupicidal effects after 24 h of exposure; however, the highest larval and pupal mortality was found in the leaf extract of methanol C. papaya against the first- to fourth-instar larvae and pupae of values LC(50) = I instar was 51.76 ppm, II instar was 61.87 ppm, III instar was 74.07 ppm, and IV instar was 82.18 ppm, and pupae was 440.65 ppm, respectively, and bacterial insecticide, spinosad against the first to fourth instar larvae and pupae of values LC(50) = I instar was 51.76 ppm, II instar was 61.87 ppm, III instar was 74.07 ppm, and IV instar was 82.18 ppm, and pupae was 93.44 ppm, respectively. Moreover, combined treatment of values of LC(50) = I instar was 55.77 ppm, II instar was 65.77 ppm, III instar was 76.36 ppm, and IV instar was 92.78 ppm, and pupae was 107.62 ppm, respectively. No mortality was observed in the control. The results that the leaves extract of C. papaya and bacterial insecticide, Spinosad is promising as good larvicidal and pupicidal properties of against chikungunya vector, A. aegypti. This is an ideal eco-friendly approach for the control of chikungunya vector, A. aegypti as target species of vector control programs.

http://www.researchgate.net/publication/51487334_Bioefficacy_of_larvicdial_and_pupicidal_properties_of_Carica_papaya_(Caricaceae)_leaf_extract_and_bacterial_insecticide_spinosad_against_chikungunya_vector_Aedes_aegypti_(Diptera_Culicidae)

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-Kalimuthu Kovendan
Bharathiar University, Coimbatore